轉化生長因子β活化激酶1Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activateAnti-TAK1/MAP3K7
360TIYO.COM-上海田源公司

抗體來源于：（Rabbit）

轉化生長因子β活化激酶1的性能參數：

中文名稱：轉化生長因子β活化激酶1
英文名稱：Anti-TAK1/MAP3K7
別名：Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activate
包裝號：G2012
產地：中國大陸/進口產品
商標/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供應商：田源試劑 TR、新試劑 NR

轉化生長因子β活化激酶1的質量標準:

■交叉反應：	hu, mo, rat, pig, hrs, cow, chk, Rb
■產品類型：	一抗
■應用領域:	/腫瘤/免疫學/信號轉導/細胞凋亡/轉錄調節因子/激酶和磷酸酶
■蛋白分子：	predicted molecular weight: 67kDa
■濃度值：	1mg/1ml
■物理性狀：	Lyophilized or Liquid
■免疫原：	KLH conjugated KLH conjugated synthetic peptide derived from human MAP3K7
■亞型：	polyclonal
■純化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
■應用技術：	//WB=1:100-500//ELISA=1:500-1000//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蠟切片需做抗原修復）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存環境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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■■產品介紹：
TAK1 （or MAP3K7） was shown to participate in regulation of transcription by transforming growth factor beta （TGF beta）. TAK1 is stimulated in response to TGF beta and bone morphogenetic protein. These results suggest that TAK1 functions as a mediator in the signaling pathway of TGF beta superfamily members. TAB1 and TAB2 are TAK1 binding proteins that may function as activators of the TAK1 （TGF b activated kinase 1） MAPKKK in TGF b signal transduction. TAB1 induced TAK1 activation promoted the dissociation of active forms of IKKa and IKK b from active TAK1, whereas the IKK mutants remained to interact with active TAK1. TNF a activated endogenous TAK1, and the kinase negative TAK1 acted as a dominant negative inhibitor against TNF a induced NFkB activation. TAK1 was suggested to act as a regulatory kinase of IKKs.

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1mg/1ml轉化生長因子β活化激酶1Anti-TAK1/MAP3K7Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activate的相關產品：免疫組化常用試劑免疫印跡常用試劑各種標記二抗