| 供貨周期 | 現貨 | 規格 | T-25 Flask |
|---|---|---|---|
| 貨號 | CBP74137 | 應用領域 | 生物產業 |
CD161 Effector Reporter Cell
| I. Background | |
NK 細胞受體(Natural killer -cell receptor, NKRs)表達于 NK 細胞和 T 細胞表面，參與調 節下游信號的激活和抑制，積極參與免疫應答的調節。它們具有 C 型凝集素樣結構域，該 結構域失去了結合 Ca 2+的能力，參與蛋白質-蛋白質相互作用，而不是碳水化合物結合。 | |
| II. Description | |
CD161 Effector Reporter Cell 報告基因藥靶模型很好的模擬了體內 CD161 的信號轉導 過程，原理見下圖所示。
| |
| III. Introduction | |
| Expressed gene: | CD161 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | RPMI-1640+10%FBS+800 μg/ml hygromycin+1 μg/ml puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional(Report Gene) Assay |
| IV. Representative Data | |
Figure 1. Dose Response of CD161 Blocking Antibody in CD161 Effector Reporter Cell (C) With CLEC2D aAPC Cell. | |
CD161 Effector Reporter Cell
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