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目錄:愛必信(上海)生物科技有限公司>>細胞生物學>>重組蛋白>> abs04204TGFB1蛋白

TGFB1蛋白
  • TGFB1蛋白
參考價 1323
訂貨量 ≥1
具體成交價以合同協議為準
1323
≥1
具體成交價以合同協議為準
  • 品牌 absin
  • 型號 abs04204
  • 廠商性質 生產商
  • 所在地 上海市
屬性

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更新時間:2025-06-12 07:49:19瀏覽次數:2216評價

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CAS - 純度 Greater than 95% as determined by reduci
分子量 - 分子式 -
供貨周期 現貨 規格 10ug;50ug;1mg
貨號 abs04204 應用領域 生物產業,綜合
主要用途 -
Recombinant Human Transforming Growth Factor beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed.

產品描述:Recombinant Human Transforming Growth Factor beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed.

別名:TGFB1蛋白;Transforming Growth Factor Beta-1, TGF-Beta-1, Latency-Associated Peptide, LAP, TGFB1, TGFB

來源:CHO Stable Cells

形態:Lyophilized from a 0.2 μm filtered solution of 50mM Glycine-HCl, 150mMNacl, pH2.5.

序列:ALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALY NQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS

內毒素水平:Less than 0.01 EU/ug as determined by LAL test.

活性:Measured by its ability to inhibit the IL-4-dependent proliferation of TF?1 human erythroleukemic cells. The ED50 for this effect is 4-40 pg/ml.

溶解方法:Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

保存方法:Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

背景說明:Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.

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