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xona 神經(jīng)元突觸細(xì)胞微灌流系統(tǒng)的基底材料的拓?fù)湫蚊彩怯绊懠?xì)胞行為的重要因素之一,細(xì)胞與微納米結(jié)構(gòu)圖案表面相互作用研究在細(xì)胞生物學(xué)、再生醫(yī)學(xué)和組織工程領(lǐng)域具有重要的意義。材料表面微納米圖案化不但可以提供結(jié)構(gòu)模版,用以研究細(xì)胞對(duì)生長環(huán)境的響應(yīng)特性,而且可以為組織再生用支架和植入性器件的設(shè)計(jì)提供基礎(chǔ)數(shù)據(jù)。
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Description of Neuron Device in DetailNat Methods. 2005 Aug;2(8):599-605.A microfluidic culture platform for CNS axonal injury, regeneration and transport.Taylor AM, Blurton-Jones M, Rhee SW, Cribbs DH, Cotman CW, Jeon NL.100umNeuronThe Neuron Device offered by Xona Microfluidics LLC is fabricated out of optically transparent and biologically inert Polydimethylsiloxane (PDMS). The Neuron Device consists of two chambers connected by microgrooves.The neuron device also makes it possible for the researcher to fluidically isolate cell bodies from axons. The device consists of two chambers connected by a much smaller microgroove barrier. The hydrostatic pressure between the two chambers separated by the microgrooves allows the researcher to fluidically isolate each chamber. This is accomplished by keeping the volumes in the wells on one side of the device higher than the other side of the device. The difference in volume creates hydrostatic pressure thus fluidically isolating each compartment.The total volume of the device is about 600 ul thus the researcher uses less of the expensive reagents typically used in neuronal culture.The neuron device also makes it possible to perform axotomy, cutting axons via vacuum aspiration in the distal chamber and observing their regrowth.xona microfluidics llc snd150 神經(jīng)元突觸細(xì)胞微灌流系統(tǒng)xona microfluidics llc snd450 神經(jīng)元突觸細(xì)胞微灌流系統(tǒng)xona microfluidics llc snd900 神經(jīng)元突觸細(xì)胞微灌流系統(tǒng)xona microfluidics llc TCND500 神經(jīng)元突觸細(xì)胞微灌流系統(tǒng)xona microfluidics llc TCND1000 神經(jīng)元突觸細(xì)胞微灌流系統(tǒng)xona microfluidics llc RD150 神經(jīng)元突觸細(xì)胞微灌流系統(tǒng)xona microfluidics llc RD450 神經(jīng)元突觸細(xì)胞微灌流系統(tǒng)xona microfluidics llc RD900 神經(jīng)元突觸細(xì)胞微灌流系統(tǒng)xona microfluidics llc ULP 神經(jīng)元突觸細(xì)胞微灌流系統(tǒng)