亚州一区二区三区中文字幕国产精品-日韩人妻一区二区三区蜜桃视频-亚洲中文字幕久久无码精品-午夜精品亚洲一区二区三区嫩草-日韩人妻一区二区三区蜜桃视频-国产一区二区精品高清在线观看-国产欧美日韩综合精品一区二区

Source

Mouse

Applications

IHC

Reactivity

Human,Rat,Mouse

Dilution

IHC 1:100-200

Storage

-20°C/1 year

Specificity

ATM protein detects endogenous levels of ATM

Source/Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen

Recombinant Protein of ATM of ATM

Uniprot No

Q13315

Alternative names

ATM

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Monoclonal

Isotype

IgG

Background

ATM serine/threonine kinase(ATM) Homo sapiens The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010],

Other

ATM, ATM

Concentration

1 mg/ml