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Bmi-1 Rabbit rabbit pAb(F270)
  • Bmi-1 Rabbit rabbit pAb(F270)
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更新時間:2025-06-28 11:44:21

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  • Source

    Rabbit

  • Applications

    WB

  • Reactivity

    Human

  • Dilution

    WB 1:500-2000

  • Storage

    -20°C/1 year

  • Specificity

    This antibody detects endogenous levels of human Bmi-1

  • Source/Purification

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • Immunogen

    Recombinant Protein derived from human Bmi-1

  • Uniprot No

    P35226

  • Alternative names

    Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    BMI1 proto-oncogene, polycomb ring finger(BMI1) Homo sapiens This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015],

  • Other

    BMI1 PCGF4 RNF51, Bmi-1

  • Concentration

    1 mg/ml

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