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Bcl-x (phospho Thr115) rabbit pAb
  • Bcl-x (phospho Thr115) rabbit pAb
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更新時間:2025-06-28 12:48:47

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SourceRabbitApplicationsIHC,ELISAReactivityHuman,Mouse,RatDilutionIHC:1:100-1:300
  • Source

    Rabbit

  • Applications

    IHC,ELISA

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    IHC: 1:100 - 1:300. ELISA: 1:5000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Phospho-Bcl-x (T115) Polyclonal Antibody detects endogenous levels of Bcl-x protein only when phosphorylated at T115.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human BCL-XL around the phosphorylation site of Thr115. AA range:81-130

  • Uniprot No

    Q07817

  • Alternative names

    BCL2L1; BCL2L; BCLX; Bcl-2-like protein 1; Bcl2-L-1; Apoptosis regulator Bcl-X

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    BCL2 like 1(BCL2L1) Homo sapiens The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. [provided by RefSeq, Dec 2015],

  • Other

    BCL2L1, Bcl-2-like protein 1

  • Mol.Wt (Da)

    26049

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

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