銅轉運蛋白CUTC抗體
參考價 | ¥ 16 |
訂貨量 | ≥1 |
- 公司名稱 上海一研生物科技有限公司
- 品牌 Genway Biotech/美國
- 型號
- 產地 進口、國產
- 廠商性質 經銷商
- 更新時間 2017/8/31 20:21:44
- 訪問次數 2864
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英文名稱 Anti-CUTC
中文名稱
別 名 CGI 32; CGI32; Copper homeostasis protein cutC homolog; cutC; CutC copper transporter homolog (E. coli); CUTC_HUMAN; RP11-483F11.3.
濃 度 1mg/1ml
規 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應 Human, Mouse, Rat
產品類型 一抗
研究領域 腫瘤 細胞生物 轉運蛋白 新陳代謝
蛋白分子量 predicted molecular weight: 29kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human CUTC
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Soium zde, Constituents: 1% BSA, 0.01M PBS, pH 7.4
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產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 Copper is an essential micronutrient used as a co-factor for several essential enzymes in all living organisms. Due to the high toxicity of copper, its metabolism is tightly regulated and defects in this regulation can cause Menkes (deficiency) or Wilson (accumulation) disease in various tissue. CUTC (cutC copper transporter homolog (E. coli)), also known as CGI-32, is a 273 amino acid protein belonging to the cutC family. CUTC is involved in copper homeostasis and is encoded by a gene located on human chromosome 10, which contains over 800 genes and 135 million nucleotides. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. Other chromosome 10 associated disorders include Cockayne syndrome, tetrahydrobiopterin deficiency and trisomy 10.
Function : May play a role in copper homeostasis. Can bind one Cu(1+) per subunit.
Subunit : Homotetramer.
Subcellular Location : Cytoplasm. Nucleus. The overexpressed protein is detected in the cytoplasm, and depending on the cell line, also in the nucleus.
Tissue Specificity : Ubiquitous.
Similarity : Belongs to the CutC family.
Database links : UniProtKB/Swiss-Prot: Q9NTM9.1
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